Testosterone Therapy: Safety Reassurance for Men from Recent Study

by | Oct 1, 2023 | General

Health Blog: General
October 1, 2023

In a world where health and wellness trends constantly evolve, one topic has gained significant attention in recent years: testosterone therapy. Amidst the buzz surrounding this treatment, questions and concerns about its cardiovascular safety have loomed large. Enter the Testosterone Replacement Therapy for Assessment of Long-term Vascular Events and Efficacy Response in Hypogonadal Men (TRAVERSE) study—a groundbreaking investigation that promises to shed light on the relationship between testosterone therapy and heart health.

The TRAVERSE Study: A Game-Changer in Testosterone Therapy

What is Hypogonadism?

Before we dive into the TRAVERSE study’s findings, let’s start with some basics. Hypogonadism, also known as low testosterone, is a condition that affects both men and women, though it’s more commonly associated with men. It occurs when the body doesn’t produce enough testosterone, the hormone responsible for various critical functions, including energy levels, muscle mass, and mental clarity.

The Concerns About Testosterone Therapy

As we age, our testosterone levels naturally decline, leading to a range of symptoms that impact our quality of life. This has prompted many individuals to explore testosterone-replacement therapy. However, concerns have lingered, particularly regarding its potential cardiovascular risks.

The TRAVERSE Study Unveiled



Key Research Details

The TRAVERSE study sought to address these concerns comprehensively. It was a randomized, double-blind, placebo-controlled trial conducted at multiple clinical trial sites in the United States. The study enrolled 5,246 men aged 45 to 80, all of whom had preexisting cardiovascular disease or a high risk of it and reported symptoms of hypogonadism.

Primary Focus: Cardiovascular Events

The primary goal of the TRAVERSE study was to assess whether testosterone-replacement therapy led to a higher incidence of major adverse cardiac events, including cardiovascular-related deaths, nonfatal heart attacks, and nonfatal strokes, compared to a placebo group.

The Results: Reassurance for Men

The TRAVERSE study’s findings, presented at ENDO 2023 and published in the prestigious New England Journal of Medicine, provide reassuring insights. Among the 5,198 patients who received either testosterone or a placebo for an average of 22 months, testosterone-replacement therapy did not result in a greater number of major cardiac events than the placebo.

It’s worth noting that major cardiac events occurred in 7.0% of the testosterone group and 7.3% of the placebo group, highlighting the importance of individualized medical guidance when considering testosterone therapy.

Implications and Cautions

While the TRAVERSE study offers promising evidence regarding the cardiovascular safety of testosterone therapy for middle-aged and older men with hypogonadism and cardiovascular risk factors, caution is still advised.

Dr. Michael Lincoff, TRAVERSE’s lead author, emphasizes that testosterone deficiency is not a life-threatening condition. Uncertainty about cardiovascular outcomes has influenced treatment decisions for clinicians and patients. Therefore, the study’s findings may facilitate a more informed consideration of the potential benefits and risks of testosterone therapy within this specific demographic.

A Growing Concern

The issue of low testosterone, often referred to as “low T,” has been on the rise among aging men. A study published in JAMA Internal Medicine revealed that prescriptions for testosterone therapy tripled between 2001 and 2011 for men over 40. This growing trend has prompted concerns and a need for more clarity regarding the cardiovascular safety of such treatments.

The FDA’s Role

To address these concerns and the conflicting data surrounding testosterone-replacement therapy, the Food and Drug Administration (FDA) initiated a review in 2010. This came after a small placebo-controlled trial was halted due to an increased incidence of cardiovascular events among patients receiving testosterone therapy. In 2015, the FDA mandated that manufacturers of testosterone products conduct well-designed clinical trials to determine whether an increased risk of heart attack or stroke exists for men taking testosterone products.

Seeking Informed Decisions

The TRAVERSE study is a significant step towards providing much-needed clarity on the cardiovascular safety of testosterone-replacement therapy.

As Dr. Lincoff suggests that therapy should be approached cautiously. It’s crucial to consult with healthcare professionals for personalized guidance tailored to your unique health circumstances.

The Bottom Line

While the TRAVERSE study’s findings provide reassurance regarding the cardiovascular safety of testosterone therapy in a specific demographic, it’s not a one-size-fits-all solution. Each individual’s health needs are unique, and decisions about testosterone therapy should be made in consultation with a qualified healthcare provider.

As the landscape of health and wellness continues to evolve, staying informed and seeking professional guidance remains the key to making the best choices for your well-being. The TRAVERSE study is undoubtedly a valuable step towards understanding the complexities of testosterone therapy, but it’s just one piece of the puzzle.

 Exploring Testosterone Therapy Options at Elite Health Online

With the recent TRAVERSE study shedding light on the cardiovascular safety of testosterone therapy in specific demographics, you might be wondering where to turn if you’re considering this treatment. Look no further than Elite Health Online, where your well-being is our top priority.

Personalized Treatment Plans

At Elite Health Online, we understand that each individual’s health journey is unique. That’s why our approach is entirely personalized. Our team of experienced physicians and wellness experts takes the time to understand your specific needs, health history, and goals. Whether you’re a middle-aged man with hypogonadism or someone looking to optimize their hormonal balance, we create tailored treatment plans designed to help you achieve your best self.

Convenient Virtual Consultations

We know that convenience matters, and that’s why Elite Health Online offers virtual consultations. You can access our program from the comfort of your own home, eliminating the need for time-consuming office visits. Our streamlined process ensures that you receive the care and guidance you need without the hassle of traveling to a clinic.

Safety and Expert Guidance

Your health and safety are our utmost priorities. Our programs are medically supervised, giving you peace of mind that you’re in expert hands. We closely monitor your progress and adjust your treatment plan as needed to ensure you’re on the path to optimal well-being.

How to Get Started

Ready to take control of your vitality and well-being? Getting started with testosterone therapy at Elite Health Online is simple:

  1. Visit Our Website: Click here to get started.
  2. Contact Us: Have questions? Contact our friendly team at  for personalized guidance and support.

Don’t let declining testosterone levels hold you back any longer. Your journey to peak performance and well-being begins now, and Elite Health Online is here to support you every step of the way. Experience the difference of personalized care, convenience, and expert guidance today. Your best self is waiting to be unlocked.

Schedule your FREE 15 minute consultation and discover the most comprehensive and affordable wellness solutions with Elite Health! Our prices are up to 60% lower than the big box providers!

CORE: Sidebar Form (BLOG)

Hi, I'm Clay

I’m one of the founders of Elite Health. We launched EHO to help people experience the best version of themselves. 

Hit your Peak Performance.

Boost your energy, build mass, reduce joint pain, increase stamina in bed, lose weight, restore hair, and feel your best.