Human chorionic gonadotropin (HCG) is a type of luteinizing hormone (LH). Although it is a naturally occurring hormone and can help men who want to raise their testosterone, they fear bioidentical hormone replacement therapy alone might cause loss of fertility or testicular atrophy. HCG instructs the testicles to produce more testosterone.

During testosterone replacement therapy, the hypothalamus begins to reduce its production of gonadotropin-releasing hormone (GnRH), which in turn causes the pituitary gland to stop releasing LH. Because of the reduction in LH, the testicles begin to produce far less testosterone, and they start shrinking in size and volume. This condition is called “hypogonadism””.

By supplementing testosterone replacement therapy with HCG, men can augment the amount of testosterone in the body without risking infertility or hypogonadism.